OptiCogs: feasibility of a multicomponent intervention to rehabilitate people with cognitive impairment post-stroke

Pilot and Feasibility Studies · 11 authors, 6 centres

AI SUMMARY

FIDELITY 100%

POPULATIONPeople post-stroke with cognitive impairment

INTERVENTIONOptiCogs: a 6-week multicomponent intervention combining cognitive rehabilitation and physical activity, delivered via telehealth

COMPARISON

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

In a single-arm feasibility study, nine people post-stroke with cognitive impairment enrolled in a 6-week multicomponent intervention called OptiCogs.

Full summary

670 CHARS

A single-arm feasibility study assessed the OptiCogs multicomponent intervention combining cognitive rehabilitation and physical activity for people with cognitive impairment post-stroke. The 6-week telehealth-based intervention enrolled nine participants, of whom eight completed all pre- and post-intervention assessments. The response rate was 10.9%, retention was high, and adherence ranged from 50 to 75%. Physical function (PROMIS-PF) showed minimal change. The telehealth-only delivery model presented barriers to recruitment and engagement. These preliminary findings suggest feasibility but require further testing in a larger pilot randomized controlled trial.

PICO

PPOPULATION

People post-stroke with cognitive impairment

IINTERVENTION

OptiCogs: a 6-week multicomponent intervention combining cognitive rehabilitation and physical activity, delivered via telehealth

OOUTCOME

Feasibility (recruitment, retention, adherence, adverse events, acceptability); secondary: cognitive function, fatigue, quality of life, physical function, occupational performance

STUDY TYPE

other

SPECIALTY

neurology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10583340

OptiCogs: feasibility of a multicomponent intervention to rehabilitate people with cognitive impairment post-stroke

Pilot and Feasibility Studies

READ THE FULL PAPER

ABSTRACT

Background Stroke is a leading cause of death and disability worldwide. Despite the prevalence and associated burden of cognitive impairment post-stroke, there is uncertainty regarding optimal cognitive rehabilitation for people post-stroke. This study aimed to assess whether a multicomponent intervention, called OptiCogs, is feasible, acceptable, and safe for people with cognitive impairment post-stroke. A secondary aim was to explore changes in cognitive function, fatigue, quality of life, physical function, and occupational performance, from pre-intervention to post-intervention. Methods A feasibility study was conducted where people post-stroke with cognitive impairment enrolled in a 6-week multicomponent intervention. The primary outcomes recorded included response rate, recruitment rate, retention rate, adherence to the intervention protocol, adverse events, and acceptability of the intervention to people post-stroke. Secondary outcomes included (i) change in cognitive functioning using the Addenbrooke’s Cognitive Examination III, (ii) fatigue using the Fatigue Severity scale, (iii) quality of life using the Stroke Specific Quality of Life scale (iv) physical function using the patient-reported outcomes measurement information system, and (v) patient-reported occupational performance using the Canadian Occupational Performance Measure. The Consolidated Standards of Reporting Trials extension reporting guidelines were followed, for pilot and feasibility studies, to standardize the conduct and reporting of this study. Results The response rate was 10.9%. Nine eligible participants were enrolled during the 4-month recruitment period, with eight participants completing the entire 6-week intervention, as well as the pre- and post-intervention outcome measures. There were no reported adverse events. Participants were satisfied with the intervention and found it acceptable overall. Results of the secondary outcomes were promising for cognitive function (ACE III, pre: 63.3 ± 23.9 to post: 69 ± 24.6), fatigue (FSS, pre: 52.5 ± 7.3 to post: 45.6 ± 7.2), quality of life (SSQoL, pre: 131.0 ± 26.3 to post: 169.9 ± 15.3), physical function (PROMIS-PF, pre: 15.5 ± 6.3 to post: 15.8 ± 5.3), and occupational performance (COPM performance, pre: 9.3 ± 2.3 to post: 22.9 ± 4.2) and COPM satisfaction, pre: 9.9 ± 2.1 to post: 22.7 ± 3.5). Conclusion Preliminary results suggest low-modest recruitment and high retention rates for the OptiCogs intervention. Changes in cognitive function, fatigue, quality of life, and self-reported occupational performance show improvement from pre- to post-intervention. These potential benefits require further testing in a larger pilot trial. Trial registration NCT05414539 . Supplementary Information The online version contains supplementary material available at 10.1186/s40814-023-01300-7.

CITATION EXPORT

Mairéad O’ Donoghue, Pauline Boland, Sinead Taylor et al.. OptiCogs: feasibility of a multicomponent intervention to rehabilitate people with cognitive impairment post-stroke. Pilot and Feasibility Studies. (2023). https://doi.org/10.1186/s40814-023-01300-7

AUTHORS

11 · 6 CENTRES

Mairéad O’ Donoghue, Pauline Boland, Sinead Taylor, Edel Hennessy, Eva Murphy, Siobhan Leahy, John McManus, Dominika Lisiecka, Helen Purtill, Rose Galvin, Sara Hayes

1https://ror.org/00a0n9e72grid.10049.3c0000 0004 1936 9692School of Allied Health, Faculty of Education and Health Sciences, Ageing Research Centre, Health Research Institute, University of Limerick, Limerick, V94 T9PX Ireland
2https://ror.org/04y3ze847grid.415522.50000 0004 0617 6840Acute Stroke and Neurology Services, UL Hospitals Group, University Hospital Limerick, Limerick, Ireland
3https://ror.org/04y3ze847grid.415522.50000 0004 0617 6840Early Supported Discharge, UL Hospitals Group, University Hospital Limerick, Limerick, Ireland
4Department of Sport, Exercise and Nutrition, School of Science and Computing, Mayo Institute of Technology, Dublin Road, GalwayGalway, Ireland
5grid.510393.d0000 0004 9343 1765Department of Nursing and Healthcare Sciences, School of Health and Social Sciences, Munster Technological University Kerry Campus, Kerry, Ireland
6https://ror.org/00a0n9e72grid.10049.3c0000 0004 1936 9692Department of Mathematics and Statistics, University of Limerick, Limerick, Ireland