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TL;DR
The authors describe ROS sources including mitochondrial metabolism and enzymes such as xanthine oxidase, and endogenous defenses including superoxide dismutase, catalase, and glutathione peroxidases.
Pharmaceuticals · 5 authors, 3 centres
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The authors describe ROS sources including mitochondrial metabolism and enzymes such as xanthine oxidase, and endogenous defenses including superoxide dismutase, catalase, and glutathione peroxidases.
The authors describe ROS sources including mitochondrial metabolism and enzymes such as xanthine oxidase, and endogenous defenses including superoxide dismutase, catalase, and glutathione peroxidases. A key challenge noted is demonstrating efficacy of antioxidant treatments and achieving adequate ocular bioavailability through topical or oral routes, particularly across the corneal epithelium and blood-ocular barrier. The authors conclude that maintaining optimal eye health requires combining preventive measures with interventional medicine using active ingredients possessing antioxidant properties.