Frontiers in Chemistry · 8 authors, 8 centres
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The human body employs endogenous antioxidant defense mechanisms involving enzymatic activities such as superoxide dismutase, catalase, and glutathione peroxidase, supplemented by dietary antioxidants from sources including vegetable oils, nuts, seeds, leafy vegetables, and fresh fruits.
The human body employs endogenous antioxidant defense mechanisms involving enzymatic activities such as superoxide dismutase, catalase, and glutathione peroxidase, supplemented by dietary antioxidants from sources including vegetable oils, nuts, seeds, leafy vegetables, and fresh fruits. The authors note that many substances showing beneficial effects in the laboratory do not work when introduced into the human body, partly due to poor bioavailability of antioxidants such as polyphenols. A key therapeutic limitation identified is that excessive antioxidant supplement consumption can cause pro-oxidant effects.
