Biomedicines · 2 authors, 2 centres
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This case report describes a 73-year-old patient with paramacular choriocapillaris atrophy showing a foveal-sparing phenotype, where central visual acuity was preserved despite surrounding atrophy. The underlying genetic pattern was unclear after testing.
The paper presents a case report of a 73-year-old patient with paramacular choriocapillaris atrophy, a rare condition. A comprehensive ophthalmological examination and diagnostic tests, including imaging and electrophysiology, were performed. Results showed preserved central visual acuity (BCVA 0.7 in the right eye, 0.6 in the left eye) and a spared fovea, with atrophy in the paramacular region. Genetic testing identified variants of uncertain significance but no clear pathogenic pattern. The discussion explores potential disease-independent mechanisms for foveal sparing, such as choroidal blood supply or cone density variations, and notes implications for prognosis and future therapeutic trial design.
