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TL;DR
The paper introduces the clinically-oriented, evidence-based, person-centered design (CORE-PCD) methodology for systematically designing connected health systems grounded in pathophysiology.
Journal of Medical Internet Research · 2 authors, 2 centres
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The paper introduces the clinically-oriented, evidence-based, person-centered design (CORE-PCD) methodology for systematically designing connected health systems grounded in pathophysiology.
This conceptual methods paper proposes the CORE-PCD methodology for designing connected health systems around an individual, organized through five steps rooted in evidence-based physiologic and pathophysiologic models. The approach leverages clinical reasoning familiar to clinicians to systematically integrate sensors, devices, and intelligence into therapeutic networks extending beyond traditional clinical interactions. A notional example illustrates application of the methodology. The authors argue the framework can expand digital therapeutics research from individual devices to networked therapeutic interventions and empower physicians to architect technology networks using clinical reasoning rather than technical expertise. The paper calls for further investigation into technology-classes, deployment configurations, and functional smart ecosystems needed for optimal care delivery.