Key mechanisms include scavenging free radicals, modulating the Nrf2 pathway, inhibiting NF-κB and MAPK signaling, and regulating CD4+ T cell differentiation.
Medicine · 2 authors, 2 centres
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Key mechanisms include scavenging free radicals, modulating the Nrf2 pathway, inhibiting NF-κB and MAPK signaling, and regulating CD4+ T cell differentiation.
Key mechanisms include scavenging free radicals, modulating the Nrf2 pathway, inhibiting NF-κB and MAPK signaling, and regulating CD4+ T cell differentiation. The authors note that while antioxidant and anti-inflammatory effects are well-supported, more in vivo research is needed to fully explore anti-tumor mechanisms. The review concludes that these natural compounds are promising for future therapeutic investigation, though the evidence is primarily preclinical and does not translate to specific clinical recommendations.