SEARCHCOHORTepidemiology, public health

cohort·epidemiology, public health, geriatrics, psychiatry, observational study·PMC10334250

Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing

JAMA Network Open · 4 authors, 4 centres

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AGENT 01 · STRUCTURED SUMMARY

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TL;DR

A lower MVPA dose than current public health guidelines (400 to <600 MET-min/wk) was associated with a reduced risk of depression.

Full summary

452 CHARS

After adjusting for multiple confounders, a negative dose-response association was observed between MVPA dose and both outcomes. The study found that an MVPA dose of 400 to less than 600 MET-min/wk was associated with a 16% lower rate of depressive symptoms and 43% lower odds of major depression. The highest activity dose (≥2400 MET-min/wk) showed the largest reductions (23% lower rate of depressive symptoms and 49% lower odds of major depression).

STUDY TYPE

cohort

SPECIALTY

epidemiology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10334250

Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing

JAMA Network Open

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ABSTRACT

Key Points Question What is the minimal dose of moderate to vigorous physical activity (MVPA) associated with a reduced risk of depression and depressive symptoms in older adults (aged ≥50 years) with and without chronic disease? Findings In this cohort study among 4016 older adults, at each of the included time points across a 10-year period, a negative dose-response association was observed between MVPA dose and depressive symptoms and major depression. Meaning The findings of this study suggest that a lower dose of MVPA than recommended from guidelines for overall health may be associated with a lower risk of depression among older adults.

CITATION EXPORT

Eamon Laird, Charlotte Lund Rasmussen, Rose Anne Kenny et al.. Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing. JAMA Network Open. (2023). https://doi.org/10.1001/jamanetworkopen.2023.22489

AUTHORS

4 · 4 CENTRES

Eamon Laird, Charlotte Lund Rasmussen, Rose Anne Kenny, Matthew P. Herring

1Physical Activity for Health Research Centre, Health Research Institute, University of Limerick, Limerick, Ireland
2The Irish Longitudinal Study on Ageing, Trinity College Dublin, Dublin, Ireland
3Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland
4Curtin School of Allied Health, Faculty of Health Sciences, Curtin University, Perth, Australia