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TL;DR
This narrative review synthesizes preclinical (in vitro and in vivo animal) data on plant monoterpenes and essential oils as potential anti-ageing agents.
Biomedicines · 4 authors, 6 centres
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This narrative review synthesizes preclinical (in vitro and in vivo animal) data on plant monoterpenes and essential oils as potential anti-ageing agents.
This narrative review synthesizes preclinical (in vitro and in vivo animal) data on plant monoterpenes and essential oils as potential anti-ageing agents. However, a major limitation noted is that most studies assess hallmarks individually rather than in an integrated ageing context, and many are conducted in settings like cancer research. The review also highlights that clinical trials are limited, sparse in pharmacokinetic data, and face challenges with compound volatility and solubility. The implications suggest monoterpenes are promising candidates for developing anti-ageing strategies, but further research using integrated ageing models and large-scale human trials is required.