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TL;DR
This systematic review synthesized evidence from four studies on post-operative colonic manometry in children with repaired anorectal malformations.
Neurogastroenterology and Motility · 7 authors, 6 centres
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This systematic review synthesized evidence from four studies on post-operative colonic manometry in children with repaired anorectal malformations.
This PRISMA-compliant systematic review searched four databases to synthesize evidence on post-operative colonic manometry in children with repaired anorectal malformations. Four eligible studies with a combined cohort of 151 children were analyzed, but only 35 underwent colonic manometry. Key findings include variable detection of high-amplitude propagated contractions (HAPCs), with one study reporting HAPCs in all children and 81% propagating to the neorectum. HAPCs were identified in 60% of children after Bisacodyl stimulation in a third study. Major limitations include insufficient reporting of surgical characteristics, bowel function, and manometric outcomes across studies, which restricts comparisons and clinical applicability.