Journal of Clinical and Translational Science · 1 author, 1 centre
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This narrative review discusses current approaches to the diagnosis, care, treatment, and vaccination of human monkeypox (Mpox), highlighting that laboratory methods such as ELISA and real-time PCR aid diagnosis, antivirals including tecovirimat, cidofovir, and brincidofovir may be effective for treatment, and vaccines such as IMVAMUNE, JYNNEOS, and MoVIHvax are under investigation for prevention.
This narrative review examines strategies for preventing and managing Mpox outbreaks, covering epidemiology, diagnosis, treatment, and vaccination. The authors describe the historical emergence of Mpox since 1970, noting an increase in incidence rate from 0.63 to 5.53 per 10,000 in the Democratic Republic of the Congo, and the rapid spread in non-endemic countries following the COVID-19 pandemic. Vaccines such as IMVAMUNE, JYNNEOS, and MoVIHvax are identified as options under investigation.
