This narrative review synthesizes human clinical evidence on primary dysmenorrhea, defining it as menstrual pain without underlying pelvic disease and describing its pathophysiology related to prostaglandins.
RBGO Gynecology & Obstetrics · 2 authors, 2 centres
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This narrative review synthesizes human clinical evidence on primary dysmenorrhea, defining it as menstrual pain without underlying pelvic disease and describing its pathophysiology related to prostaglandins.
This narrative review synthesizes evidence on primary dysmenorrhea in menstruating women. It defines the condition as colic pain during menstruation without pelvic disease, linked to increased uterine prostaglandin synthesis causing hypercontractility and ischemia. The implications focus on the importance of patient education and appropriate first-line pharmacotherapy.