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TL;DR
This is a case report describing a 48-year-old man with recurrent abdominal pain and obstruction, where primary sclerosing encapsulating peritonitis was diagnosed during surgery and treated with membrane excision and steroid therapy.
Journal of Medical Case Reports · 4 authors, 2 centres
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This is a case report describing a 48-year-old man with recurrent abdominal pain and obstruction, where primary sclerosing encapsulating peritonitis was diagnosed during surgery and treated with membrane excision and steroid therapy.
This case report details a 48-year-old man presenting with recurrent abdominal pain and chronic intestinal obstruction. Preoperative CT suggested jejunal dilatation from an internal mesenteric hernia, but exploratory surgery revealed a thick fibrous membrane encasing the small intestine, confirming primary sclerosing encapsulating peritonitis. Histopathology and immunological findings (e.g., IgG4 plasma cells, elevated IL-6) supported an immune-mediated mechanism. The case highlights the diagnostic challenge of this rare condition, the necessity of intraoperative diagnosis, and suggests that IL-6 and IgG4 may serve as potential disease activity markers, though the authors note limitations in their evidence.