This single-center retrospective study of 408 Chinese adults undergoing cardiac surgery found that a preoperative CONUT score >3 was independently associated with higher all-cause mortality and postoperative complications.
Chinese Medical Journal · 4 authors, 2 centres
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This single-center retrospective study of 408 Chinese adults undergoing cardiac surgery found that a preoperative CONUT score >3 was independently associated with higher all-cause mortality and postoperative complications.
This single-center retrospective observational study analyzed 408 Chinese adults who underwent cardiac surgery, using a CONUT score cutoff of 3 derived from preoperative serum albumin, lymphocyte count, and total cholesterol. The median follow-up was 72.12 months, 28 (6.9%) patients died, and the overall 5-year survival was 94.9%. In multivariate analysis, a high CONUT score remained an independent predictor of mortality (HR=5.973, 95% CI 1.537-23.213, P=0.010), and the joint model with CONUT, age, and hypertension had an AUC of 0.744. The high CONUT group also experienced significantly more postoperative complications (P=0.02), with CONUT independently associated with secondary outcomes (HR=16.619, 95% CI 1.484-86.120, P=0.023). The authors note limitations including the retrospective single-center Chinese design with small sample size, 178 patients lost to follow-up, lack of serial CONUT measurements, absence of data on nutritional intervention effects, and missing cardiovascular drug information.