SEARCHNARRATIVE_REVIEWpreclinical research, biomedical research

narrative_review·preclinical research, biomedical research, research methods·PMC10007050

Recent Advances in Centrifugal Spinning and Their Applications in Tissue Engineering

Polymers · 7 authors, 7 centres

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TL;DR

The review synthesizes findings on how process variables influence fiber morphology and discusses current limitations and future directions for the field.

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317 CHARS

The review covers how process variables—including concentration viscosity, molecular weight, and collector shape—affect fiber homogeneity, alignment, diameter, and web porosity. Under identical processing conditions, centrifugally spun fibers can exhibit superior mechanical properties compared to electrospun fibers.

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narrative_review

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preclinical research

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100% · A

ORIGINAL PAPER

PMC10007050

Recent Advances in Centrifugal Spinning and Their Applications in Tissue Engineering

Polymers

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ABSTRACT

Abstract Over the last decade, researchers have investigated the potential of nano and microfiber scaffolds to promote wound healing, tissue regeneration, and skin protection. The centrifugal spinning technique is favored over others due to its relatively straightforward mechanism for producing large quantities of fiber. Many polymeric materials have yet to be investigated in search of those with multifunctional properties that would make them attractive in tissue applications. This literature presents the fundamental process of fiber generation, and the effects of fabrication parameters (machine, solution) on the morphologies such as fiber diameter, distribution, alignment, porous features, and mechanical properties. Additionally, a brief discussion is presented on the underlying physics of beaded morphology and continuous fiber formation. Consequently, the study provides an overview of the current advancements in centrifugally spun polymeric fiber-based materials and their morphological features, performance, and characteristics for tissue engineering applications. Keywords: centrifugal spinning, jet trajectory, polymer solution, nanofiber, tissue engineering

CITATION EXPORT

Shaik Merkatur Hakim Marjuban, Musfira Rahman, Syeda Sharmin Duza et al.. Recent Advances in Centrifugal Spinning and Their Applications in Tissue Engineering. Polymers. (2023). https://doi.org/10.3390/polym15051253

AUTHORS

7 · 7 CENTRES

Shaik Merkatur Hakim Marjuban, Musfira Rahman, Syeda Sharmin Duza, Mohammad Boshir Ahmed, Dinesh K Patel, Md Saifur Rahman, Karen Lozano

1Department of Materials Science and Engineering, Texas A&M University, College Station, TX 77843, USA
2Department of Mechanical Engineering, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA
3Zachry Department of Civil and Environmental Engineering, Texas A&M University, College Station, TX 77840, USA
4Microbiology & Immunology Department, Holy Family Red Crescent Medical College & Hospital, Dhaka 1000, Bangladesh
5School of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea
6Department of Biosystems Engineering, Institute of Forest Science, Kangwon National University, Chuncheon 24341, Republic of Korea
7Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA