Reconstructive surgery and adjuvant radiotherapy for the multimodal approach in oral cancer: a single cancer centre experience

Annals of Medicine and Surgery · 9 authors, 5 centres

AI SUMMARY

FIDELITY 100%

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

All flaps remained clinically stable without failure over a 3-year follow-up period.

Full summary

262 CHARS

In the 3-year period after reconstruction and radiotherapy, all flaps remained clinically stable without signs of failure. The authors note that cohort studies would be necessary to better understand the role of each treatment component in the multimodal scheme.

STUDY TYPE

case_report

SPECIALTY

surgery

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10617813

Reconstructive surgery and adjuvant radiotherapy for the multimodal approach in oral cancer: a single cancer centre experience

Annals of Medicine and Surgery

READ THE FULL PAPER

ABSTRACT

Abstract Introduction and importance: Ablative surgery for oral cancer, irrespective of the histological subtype, causes large tissue defects, functional and aesthetic damage. Microsurgical free flaps have been widely used in reconstruction after resection, with satisfactory success rates in conjunction with adjuvant radiotherapy (RT). This study aims to describe our clinical institutional experience based on the multimodal treatment performed in four cases diagnosed with oral squamous cell carcinoma with the use of different microvascular free flaps and RT. Case series presentation: Four patients underwent reconstructive microsurgery after surgical resection of oral cancer, using three types of free flap: radial forearm fasciocutaneous, osteomyocutaneous fibular, and anterolateral thigh musculocutaneous flaps; RT was performed in Case 2 and Case 3. In the period of 3 years after microsurgical reconstruction and RT, flaps remain clinically stable without failure signs in full patients submitted to multimodal treatment. Clinical discussion: After resection of oral carcinomas, extensive tissue defects can be successfully treated with reconstructive microsurgery using different types of microvascular free flaps. RT for locoregional control is a feasible option and did not seem to interfere with the survival of flaps. Conclusion: An enhance long-term follow-up to assess overall and disease-free survival rates and quality of life must be carried out; however, cohort studies would be necessary for better understanding of the role of each treatment in the multimodal scheme. Keywords: adjuvant radiotherapy, mandibular reconstruction, microsurgical free flaps, oral squamous cell carcinomas, reconstructive surgical surgery

CITATION EXPORT

Wilber Edison Bernaola-Paredes, Monica Lucia Rodrigues, Henrique Perez Carvalho et al.. Reconstructive surgery and adjuvant radiotherapy for the multimodal approach in oral cancer: a single cancer centre experience. Annals of Medicine and Surgery. (2023). https://doi.org/10.1097/MS9.0000000000001357

AUTHORS

9 · 5 CENTRES

Wilber Edison Bernaola-Paredes, Monica Lucia Rodrigues, Henrique Perez Carvalho, Fernando dos Santos Bitencourt, Marcelo Carvalho Coutinho, Felipe D’Almeida Costa, Kleber Arturo Vallejo-Rosero, Jose Agustin Marquez-Zambrano, Antonio Cassio Assis Pellizzon

Departments ofaRadiation Oncology
bHead and Neck Surgery & Otorhinolaryngology
cAnatomic Pathology, A.C. Camargo Cancer Center, São Paulo, Brazil
dDepartment of Oral and Maxillofacial Surgery, Central University of Ecuador, Quito, Ecuador
eDepartment of Oral Pathology, School of Dentistry and Rehabiliation Sciences, San Sebastian University, Santiago, Chile.