SEARCHSYSTEMATIC_REVIEWpublic health, epidemiology

systematic_review·public health, epidemiology, pediatrics, obstetrics and gynecology, research methods·PMC10603613

Research funding for newborn health and stillbirths, 2011–20: a systematic analysis of levels and trends

The Lancet. Global Health · 9 authors, 7 centres

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TL;DR

Only $166·3 million (28·8%) was directed to small and vulnerable newborn research and just $8·4 million (1·5%) to stillbirth research.

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Only $166·3 million (28·8%) was directed to small and vulnerable newborn research and just $8·4 million (1·5%) to stillbirth research. Total annual active LMIC funding nearly tripled from $23·5 million in 2011 to $68·2 million in 2020.

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systematic_review

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public health

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AI pipeline

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ORIGINAL PAPER

PMC10603613

Research funding for newborn health and stillbirths, 2011–20: a systematic analysis of levels and trends

The Lancet. Global Health

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ABSTRACT

Summary Background Worldwide, an estimated 4·4 million newborn deaths and stillbirths occurred in 2020, and 98% of these deaths occurred in low-income and middle-income countries (LMICs). We aimed to analyse new research grants for newborns and stillbirth awarded by major funders in 2019–20, and all research funding allocated to LMIC-based institutions in 2011–20. Methods For this systematic analysis, we searched Dimensions, the world's largest research funding database, for grants relevant to neonatal and stillbirth research. Included grants were categorised by in-depth content analysis, with descriptive quantitative analyses by funder and recipient countries, research pipeline, topic, and year. Findings Globally, in 2019–20, major funders awarded a mean annual total of US$577·1 million per year for newborn and stillbirth research (mean total of 550 grants per year). $166·3 million (28·8%) of $577·1 million was directed to small and vulnerable newborn research, but only $8·4 million (1·5%) was directed to stillbirth research. The majority of funding, $537·0 million (93·0%), was allocated to organisations based in high-income countries. Between 2011 and 2020, LMIC-based recipients were named on 1985 grants from all funders worth $486·7 million, of which $73·1 million (15·0%) was allocated to small and vulnerable newborn research and $12·0 million (2·5%) was allocated to stillbirth research. Most LMIC funding supported preclinical or observational studies ($236·8 million [48·7%] of $486·7 million), with implementation research receiving only $13·9 million (2·9%). Interpretation Although investment in research related to neonatal health and stillbirths has increased between 2011 and 2020, there are marked disparities in distribution geographically, between major causes of mortality, and among research pipeline types. Stillbirth research received minimal funding in both high-income countries and LMICs, despite a similar number of deaths compared with neonates. Direct investment in LMIC-led research, especially for implementation research, could accelerate the slow global progress on stillbirth prevention and newborn survival. Funding None. Translations For the French, German and Spanish translations of the abstract see Supplementary Materials section.

CITATION EXPORT

Priyesh Agravat, Eva M Loucaides, Meghan Bruce Kumar et al.. Research funding for newborn health and stillbirths, 2011–20: a systematic analysis of levels and trends. The Lancet. Global Health. (2023). https://doi.org/10.1016/S2214-109X(23)00379-0

AUTHORS

9 · 7 CENTRES

Priyesh Agravat, Eva M Loucaides, Meghan Bruce Kumar, Anna Howells, Alexandra Molina García, Ismail Sebina, Núria Balanza, Elizabeth J A Fitchett, Joy E Lawn

aSt George's, University of London, London, UK
bLondon School of Hygiene & Tropical Medicine, London, UK
cKEMRI-Wellcome Trust, Nairobi, Kenya
dKing's College Hospital NHS Foundation Trust, London, UK
eCentro de Salud San Fernando, Servicio Madrileño de Salud, Madrid, Spain
fQIMR Berghofer Medical Research Institute, Herston, QLD, Australia
gISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain