SEARCHOTHERpublic health, obstetrics and gynecology

other·public health, obstetrics and gynecology, pediatrics, epidemiology, research methods·PMC10472017

Research prioritisation on prevention and management of preterm birth in low and middle-income countries (LMICs) with a special focus on Bangladesh using the Child Health and Nutrition Research Initiative (CHNRI) method

Journal of Global Health · 23 authors, 8 centres

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TL;DR

This study used the CHNRI expert-prioritization method to identify the most important research questions for preventing and managing preterm birth in low- and middle-income countries, with a focus on Bangladesh. The top-ranked priorities were primarily health systems and policy research questions aimed at improving the implementation and uptake of existing interventions like Kangaroo Mother Care (KMC) and breastfeeding.

Full summary

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The study employed the Child Health and Nutrition Research Initiative (CHNRI) method, a structured expert prioritization exercise. Seventy-six experts generated 490 research questions, which were collated into 95 unique questions. The results generated a ranked list of research priorities for low- and middle-income countries (LMICs) and Bangladesh. Health systems and policy research dominated the top 20 priorities, focusing on understanding and improving the delivery and uptake of interventions like facility and community-based Kangaroo Mother Care (KMC), promoting breastfeeding, and improving referral networks. The central implication is that research to improve the implementation and scaling-up of existing, evidence-based care for preterm infants is critical to reducing mortality and meeting Sustainable Development Goal targets.

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other

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public health

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AI pipeline

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ORIGINAL PAPER

PMC10472017

Research prioritisation on prevention and management of preterm birth in low and middle-income countries (LMICs) with a special focus on Bangladesh using the Child Health and Nutrition Research Initiative (CHNRI) method

Journal of Global Health

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ABSTRACT

Abstract Background Fifteen million babies are born preterm globally each year, with 81% occurring in low- and middle-income countries (LMICs). Preterm birth complications are the leading cause of newborn deaths and significantly impact health, quality of life, and costs of health services. Improving outcomes for newborns and their families requires prioritising research for developing practical, scalable solutions, especially in low-resource settings such as Bangladesh. We aimed to identify research priorities related to preventing and managing preterm birth in LMICs for 2021-2030, with a special focus on Bangladesh. Methods We adopted the Child Health and Nutrition Research Initiative (CHNRI) method to set research priorities for preventing and managing preterm birth. Seventy-six experts submitted 490 research questions online, which we collated into 95 unique questions and sent for scoring to all experts. A hundred and nine experts scored the questions using five pre-selected criteria: answerability, effectiveness, deliverability, maximum potential for burden reduction, and effect on equity. We calculated weighted and unweighted research priority scores and average expert agreement to generate a list of top-ranked research questions for LMICs and Bangladesh. Results Health systems and policy research dominated the top 20 identified priorities for LMICs, such as understanding and improving uptake of the facility and community-based Kangaroo Mother Care (KMC), promoting breastfeeding, improving referral and transport networks, evaluating the impact of the use of skilled attendants, quality improvement activities, and exploring barriers to antenatal steroid use. Several of the top 20 questions also focused on screening high-risk women or the general population of women, understanding the causes of preterm birth, or managing preterm babies with illnesses (jaundice, sepsis and retinopathy of prematurity). There was a high overlap between research priorities in LMICs and Bangladesh. Conclusions This exercise, aimed at identifying priorities for preterm birth prevention and management research in LMICs, especially in Bangladesh, found research on improving the care of preterm babies to be more important in reducing the burden of preterm birth and accelerating the attainment of Sustainable Development Goal 3 target of newborn deaths, by 2030.

CITATION EXPORT

Shumona Sharmin Salam, Shafiqul Ameen, Julie Balen et al.. Research prioritisation on prevention and management of preterm birth in low and middle-income countries (LMICs) with a special focus on Bangladesh using the Child Health and Nutrition Research Initiative (CHNRI) method. Journal of Global Health. (2023). https://doi.org/10.7189/jogh.13.07004

AUTHORS

23 · 8 CENTRES

Shumona Sharmin Salam, Shafiqul Ameen, Julie Balen, Quamrun Nahar, Sabrina Jabeen, Anisuddin Ahmed, Bronwen Gillespie, Lawrence Chauke, Abdul Mannan, Mahbubul Hoque, Sanjoy Kumer Dey, Jahurul Islam, Sabina Ashrafee, Husam Md Shah Alam, Ashfia Saberin, Palash Kumar Saha, Supriya Sarkar, Azizul Alim, Muhammad Shariful Islam, Clive Gray, Shams El Arifeen, Ahmed Ehsanur Rahman, Dilly OC Anumba

1The University of Sheffield, Sheffield, UK
2International Centre for Diarrhoeal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh
3Canterbury Christ Church University, Canterbury, UK
4University of the Witwatersrand, Johannesburg, South Africa
5Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
6Dhaka Shishu (Children) Hospital, Dhaka, Bangladesh
7Directorate General of Health Services (DGHS), Government of Bangladesh, Ministry of Health and Family Welfare, Bangladesh
8Stellenbosch University, Stellenbosch, South Africa