SEARCHNARRATIVE_REVIEWophthalmology, retina

narrative_review·ophthalmology, retina, glaucoma, dry eye, endocrinology·PMC10828665

Research progress on ocular complications caused by type 2 diabetes mellitus and the function of tears and blepharons

Open Life Sciences · 3 authors, 2 centres

AI SUMMARY

FIDELITY 100%

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

“

TL;DR

Full summary

391 CHARS

The review also analyzes the relationship between OCs and the protective functions of tears and blepharons, noting that OCs can disrupt tear film homeostasis and lead to conditions like xerophthalmia. The primary limitation is that as a narrative review, it does not present new empirical data but consolidates existing research to provide theoretical guidance for prevention and management.

STUDY TYPE

narrative_review

SPECIALTY

ophthalmology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10828665

Research progress on ocular complications caused by type 2 diabetes mellitus and the function of tears and blepharons

Open Life Sciences

READ THE FULL PAPER

ABSTRACT

Abstract The purpose of this study was to explore the related research progress of ocular complications (OCs) caused by type 2 diabetes mellitus (T2DM), tear and tarsal function, and the application of deep learning (DL) in the diagnosis of diabetes and OCs caused by it, to provide reference for the prevention and control of OCs in T2DM patients. This study reviewed the pathogenesis and treatment of diabetes retinopathy, keratopathy, dry eye disease, glaucoma, and cataract, analyzed the relationship between OCs and tear function and tarsal function, and discussed the application value of DL in the diagnosis of diabetes and OCs. Diabetes retinopathy is related to hyperglycemia, angiogenic factors, oxidative stress, hypertension, hyperlipidemia, and other factors. The increase in water content in the corneal stroma leads to corneal relaxation, loss of transparency, and elasticity, and can lead to the occurrence of corneal lesions. Dry eye syndrome is related to abnormal stability of the tear film and imbalance in neural and immune regulation. Elevated intraocular pressure, inflammatory reactions, atrophy of the optic nerve head, and damage to optic nerve fibers are the causes of glaucoma. Cataract is a common eye disease in the elderly, which is a visual disorder caused by lens opacity. Oxidative stress is an important factor in the occurrence of cataracts. In clinical practice, blood sugar control, laser therapy, and drug therapy are used to control the above eye complications. The function of tear and tarsal plate will be affected by eye diseases. Retinopathy and dry eye disease caused by diabetes will cause dysfunction of tear and tarsal plate, which will affect the eye function of patients. Furthermore, DL can automatically diagnose and classify eye diseases, automatically analyze fundus images, and accurately diagnose diabetes retinopathy, macular degeneration, and other diseases by analyzing and processing eye images and data. The treatment of T2DM is difficult and prone to OCs, which seriously threatens the normal life of patients. The occurrence of OCs is closely related to abnormal tear and tarsal function. Based on DL, clinical diagnosis and treatment of diabetes and its OCs can be carried out, which has positive application value. Keywords: type 2 diabetes mellitus, ocular complications, tears, blepharons, deep learning, research progress

CITATION EXPORT

Xiaohong Wang, Jian Fang, Lina Yang. Research progress on ocular complications caused by type 2 diabetes mellitus and the function of tears and blepharons. Open Life Sciences. (2024). https://doi.org/10.1515/biol-2022-0773

AUTHORS

3 · 2 CENTRES

Xiaohong Wang, Jian Fang, Lina Yang

1 Department of Operating Room, Xinchang County Peoples Hospital, Xinchang, 312500, Shaoxing City, Zhejiang, China
2 Department of Ophthalmolgy, Xinchang County Peoples Hospital, Xinchang, 312500, Shaoxing City, Zhejiang, China