Results of Nailfold Videocapillaroscopy in Patients with Pseudoexfoliative Glaucoma

Life · 6 authors, 3 centres

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TL;DR

This cohort study compared nailfold videocapillaroscopy (NVC) findings between 39 patients with pseudoexfoliative glaucoma (XFG) and 32 healthy controls, finding that specific capillaroscopic features like tortuosity and microhemorrhages differ between XFG subtypes and controls.

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This observational cohort study compared nailfold videocapillaroscopy (NVC) findings in 39 patients with pseudoexfoliative glaucoma (XFG) and 32 age- and gender-matched healthy controls. The XFG group was further divided into hypertensive (hXFG, n=29) and normotensive (nXFG, n=10) subgroups. The study found no statistically significant difference in the overall rate of an abnormal NVC pattern between the XFG and control groups (p=0.8773). 6.25%, p=0.0520). A prevalent number of tortuous capillaries was observed in hXFG patients with advanced glaucomatous neuropathy. No significant correlations were found between NVC results and clinical parameters like age, intraocular pressure, or visual field defect.

STUDY TYPE

cohort

SPECIALTY

ophthalmology

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100% · A

ORIGINAL PAPER

PMC10144131

Results of Nailfold Videocapillaroscopy in Patients with Pseudoexfoliative Glaucoma

Life

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ABSTRACT

The aim of this study was to evaluate the nailfold videocapillaroscopic examination results from patients with pseudoexfoliative glaucoma (XFG) and to assess the relationship between the results of this examination and the patient’s clinical status in the XFG group. Material and Methods: The studied group consisted of 39 Caucasian patients with XFG and 32 patients in a control group. The patients were classified into two subgroups: the hypertensive pseudoexfoliative glaucoma (hXFG) subgroup and the normotensive pseudoexfoliative glaucoma (nXFG) subgroup. The nailfold videocapillaroscopy (NVC) was performed on all participants. The results of each NVC were classified as having a normal or abnormal pattern. Results: There was no statistical difference between the results of an abnormal NVC pattern in the study group vs. the control group ( p = 0.8773). Microhemorrhages were shown in 30.0% of patients with nXFG vs. the control group (6.25%) ( p = 0.0520). Microhemorrhages tended to be more frequent in the XFG group ( p = 0.1221). A prevalent number of tortuous capillaries was observed in hXFG patients with advanced glaucomatous neuropathy. Dilatation in the capillaries and microbleedings were observed in the group of patients with lower IOP values. Tortuosity in the capillaries was significantly more frequent in PEXG patients (XFG vs. control: p = 0.0386). No relationships between the results of NVC and age, c/d, BCVA, time of treatment, and visual field defect were found. Conclusions: Specific features of NVC examination differentiate nXFG from hXFG patients. Some capillaroscopic features may correlate with the patient’s clinical status of XFG.

CITATION EXPORT

Urszula Łukasik, Joanna Bartosińska, Ewa Kosior-Jarecka et al.. Results of Nailfold Videocapillaroscopy in Patients with Pseudoexfoliative Glaucoma. Life. (2023). https://doi.org/10.3390/life13040967

AUTHORS

6 · 3 CENTRES

Urszula Łukasik, Joanna Bartosińska, Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Dorota Krasowska, Tomasz Żarnowski

1Department of Diagnostics and Microsurgery of Glaucoma, Medical University of Lublin, 20-079 Lublin, Poland
2Department of Cosmetology and Aesthetic Medicine, Medical University of Lublin, 20-093 Lublin, Poland
3Department of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, 20-093 Lublin, Poland

EDITOR / REVIEWER

Akio Oishi