It found that male sex and Black race were associated with higher odds of admission for HHS compared to DKA, and HHS admissions had greater severity of illness and mortality.
Pediatric Diabetes · 4 authors, 6 centres
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It found that male sex and Black race were associated with higher odds of admission for HHS compared to DKA, and HHS admissions had greater severity of illness and mortality.
This study used a retrospective analysis of the Kids' Inpatient Database from 2006, 2009, 2012, and 2019 to identify 8,961 pediatric admissions for DKA or HHS in youth with type 2 diabetes. Descriptive statistics and logistic regression were used to compare characteristics. The central result is that in adjusted models, males had 1.77-fold higher odds (95% CI 1.42–2.21) and Black patients had 1.81-fold higher odds (95% CI 1.34–2.44) of HHS admission versus DKA. HHS admissions were associated with 11.3-fold higher odds for major or extreme severity of illness and 5.0-fold higher odds for mortality compared to DKA. The findings suggest distinct risk profiles and higher acuity for HHS in this population.