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TL;DR
This editorial introduces a Special Issue of eight papers (two original research articles, five reviews, one case report) covering molecular and cellular mechanisms, biomarkers, and emerging therapies for various ocular diseases.
International Journal of Molecular Sciences · 1 author, 1 centre
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This editorial introduces a Special Issue of eight papers (two original research articles, five reviews, one case report) covering molecular and cellular mechanisms, biomarkers, and emerging therapies for various ocular diseases.
This narrative editorial summarizes a Special Issue of the International Journal of Molecular Sciences containing eight papers on ocular disease pathophysiology and emerging therapies. Two reviews examine diabetic retinopathy pathogenesis in relation to dietary patterns and vitamin D supplementation. One review covers retinal diseases linked to C2orf71/PCARE mutations. A case report describes concurrent macrophage activation syndrome and retinal vasculitis in systemic lupus erythematosus. Original research by Hat et al. quantified sex steroid hormone receptor mRNA in human lacrimal glands, finding that ERα mRNA expression was significantly higher than AR and ERβ. Another original study by Schlegel et al. characterized the ocular surface microbiome and tear proteome in dry eye disease. A review by Kaštelan et al. identified candidate tear biomarkers for Alzheimer's disease. Pašalić et al. reviewed genetic and epigenetic mechanisms in uveal melanoma. The editorial notes limited prospective research on dietary interventions for retinopathy and the need for further molecular studies.