Surgical Treatment in Patients with Toxic Phosphorus Osteonecrosis of Facial Skull Middle Zone

Dentistry Journal · 12 authors, 10 centres

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TL;DR

This study classified 50 patients with toxic phosphorus osteonecrosis from drug abuse into four types based on midface bone involvement and reported the results of their surgical treatment.

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111 CHARS

The study details the patient characteristics, classification system, and diagnostic workup for this condition.

STUDY TYPE

case_report

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surgery

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ORIGINAL PAPER

PMC10216904

Surgical Treatment in Patients with Toxic Phosphorus Osteonecrosis of Facial Skull Middle Zone

Dentistry Journal

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ABSTRACT

Abstract During the last few years, in the territory of the Russian Federation, the number of cases of toxic phosphoric osteonecrosis of the jaws has increased against the background of taking drugs of “artisanal” production (pervitin, desomorphin). The aim of our study was to increase the effectiveness of surgical treatment of patients with a diagnosis of toxic phosphorus necrosis of the maxilla. We performed a comprehensive treatment of patients with a history of drug addiction and the above diagnosis. Surgical intervention in the volume of complete resection of pathologically altered tissues and reconstructive techniques using local tissues and a replaced flap made it possible to achieve good aesthetic and functional results in the early and late postoperative period. Thus, our proposed method of surgical treatment can be used in similar clinical situations. Keywords: osteonecrosis of the jaws, maxilla, zygoma, orbit, substance related disorder, margins of excision, krokodil, desomorphine

CITATION EXPORT

Davit H Ispiryan, Gagik Hakobyan, Anastasia Li et al.. Surgical Treatment in Patients with Toxic Phosphorus Osteonecrosis of Facial Skull Middle Zone. Dentistry Journal. (2023). https://doi.org/10.3390/dj11050108

AUTHORS

12 · 10 CENTRES

Davit H Ispiryan, Gagik Hakobyan, Anastasia Li, Ekaterina Yu Diachkova, Yuriy Vasil’ev, Artur Kheygetyan, Elena Ivanova, Kirill Zhandarov, Natalia Kireeva, Roman Safronov, Alexey Serikov, Yuri A Medvedev

1Department of Maxillofacial Surgery, I.M. Sechenov First Moscow State Medical University (Sechenov University), 121059 Moscow, Russia
2Department of Oral and Maxillofacial Surgery, Yerevan State Medical University, Yerevan 0025, Armenia
3Department of Oral Surgery, I.M. Sechenov First Moscow State Medical University (Sechenov University), 121059 Moscow, Russia
4Department of Operative Surgery and Topographic Anatomy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia
5Dentistry Department No.1, Rostov State Medical University, 344022 Rostov-on-Don, Russia
6Department of Oral Surgery and Implantology, Vladimirsky Moscow Regional Research Clinical Institute, 129110 Moscow, Russia
7Department of Therapeutic Dentistry, FGBOU DPO RMANPO of the Ministry of Health of Russia, 125993 Moscow, Russia
8Department of Outpatient Therapy, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119333 Moscow, Russia
9Department of Physical Education, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119121 Moscow, Russia
10Department of Maxillofacial Surgery and Traumatology, A.I. Yevdokimov Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia