Allergy, Asthma & Immunology Research · 4 authors, 1 centre
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This narrative review argues that allergic diseases and asthma are prototypical 'One Health' issues, as their burden is directly and indirectly influenced by the interconnected health of humans, animals, and the environment. The authors propose that mitigating climate change and promoting an interdisciplinary One Health approach are essential to decrease the burden of these conditions.
This narrative review synthesizes evidence on the rising prevalence of allergic diseases, linking it to complex gene-environment interactions and the concept of the 'exposome.' The authors discuss how climate change, biodiversity loss, and alterations to the microbiome and diet can impact immune regulation and epithelial barriers, potentially increasing the risk of allergic sensitization and chronic inflammation. The review emphasizes that allergic diseases are prototypical One Health issues, as they are influenced by the health of ecosystems, water, soil, and air.
