SEARCHMETA-ANALYSISendocrinology, public health

meta-analysis·endocrinology, public health, systematic review, meta-analysis, epidemiology·PMC10578590

The effect of health behavior interventions to manage Type 2 diabetes on the quality of life in low-and middle-income countries: A systematic review and meta-analysis

PLOS ONE · 9 authors, 3 centres

AI SUMMARY

FIDELITY 100%

POPULATIONPeople with Type 2 diabetes mellitus in low- and middle-income countries

INTERVENTIONHealth behavior interventions including diabetes self-management education, dietary interventions, and/or physical activity interventions

COMPARISONControl groups

This summary was generated by AI from a single paper. It has not been reviewed by a clinician and is not clinical advice. Verify against the source before acting on it.

AGENT 01 · STRUCTURED SUMMARY

TRACE TO SOURCE

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TL;DR

No significant improvements were found for physical or mental component summary scores assessed separately.

Full summary

634 CHARS

Of the included studies, 31 involved diabetes self-management education and 14 included dietary and/or physical activity interventions. A random-effects meta-analysis of 25 studies showed a significant improvement in overall quality of life scores (SMD=1.62, 95%CI 0.65–2.60, p=0.001) with moderate quality evidence. However, no significant improvements were found for the physical component summary (SMD=0.76, 95%CI -0.03–1.56, p=0.060) or mental component summary (SMD=0.43, 95%CI -0.30–1.16, p=0.249) across seven studies. High heterogeneity (I²=0.96 for overall QOL) was noted, attributed to variability in QOL measurement scales.

PICO

PPOPULATION

People with Type 2 diabetes mellitus in low- and middle-income countries

IINTERVENTION

Health behavior interventions including diabetes self-management education, dietary interventions, and/or physical activity interventions

OOUTCOME

Quality of life (primary); HbA1c, fasting blood glucose, BMI, self-management behaviors (secondary)

STUDY TYPE

meta-analysis

SPECIALTY

endocrinology

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10578590

The effect of health behavior interventions to manage Type 2 diabetes on the quality of life in low-and middle-income countries: A systematic review and meta-analysis

PLOS ONE

READ THE FULL PAPER

ABSTRACT

Abstract Background Behavioral interventions targeted at managing Type 2 diabetes mellitus (T2DM) may have a positive effect on quality of life (QOL). Limited reviews have synthesized this effect in low- and middle-income countries (LMICs). This review and meta-analysis synthesised available evidence on the effect of behavioral interventions to manage T2DM on the QOL of people with T2DM in LMICs. Methods Electronic databases PUBMED/MEDLINE, SCOPUS, CINAHL, Embase, Web of Science and PsycINFO were searched from May to June 2022. Studies published between January 2000 and May 2022, conducted in LMICs using randomized controlled trial design, using a health behavior intervention for T2DM management, and reporting QOL outcomes were included. Difference in QOL change scores between the intervention and control group was calculated as the standardized mean difference (SMD) of QOL scores observed between the intervention and control groups. Random-effects model was used for meta-analysis. Results Of 6122 studies identified initially, 45 studies met the inclusion criteria (n = 8336). Of them, 31 involved diabetes self-management education and 14 included dietary and/or physical activity intervention. There was moderate quality evidence from the meta-analysis of mean QOL (n = 25) that health behavior intervention improved the QOL of people with T2DM (SMD = 1.62, 95%CI = 0.65–2.60 I 2 = 0.96, p = 0.001). However, no significant improvements were found for studies (n = 7) separately assessing the physical component summary (SMD = 0.76, 95%CI = -0.03–1.56 I 2 = 0.94, p = 0.060) and mental component summary (SMD = 0.43, 95%CI = -0.30–1.16 I 2 = 0.94, p = 0.249) scores. High heterogeneity and imprecise results across studies resulted in low to moderate quality of evidence. Conclusion The findings suggest that health behavior interventions to manage T2DM may substantially improve the QOL of individuals with T2DM over short term. However, due to low to moderate quality of evidence, further research is required to corroborate our findings. Results of this review may guide future research and have policy implications for T2DM management in LMICs.

CITATION EXPORT

Ashmita Karki, Corneel Vandelanotte, Saman Khalesi et al.. The effect of health behavior interventions to manage Type 2 diabetes on the quality of life in low-and middle-income countries: A systematic review and meta-analysis. PLOS ONE. (2023). https://doi.org/10.1371/journal.pone.0293028

AUTHORS

9 · 3 CENTRES

Ashmita Karki, Corneel Vandelanotte, Saman Khalesi, Padam Dahal, Lal B Rawal, Edward Zimbudzi, Edward Zimbudzi, Edward Zimbudzi, Edward Zimbudzi

1School of Health, Medical and Applied Sciences, Appleton Institute, Central Queensland University, Rockhampton, Australia
2Translational Health Research Institute (THRI), Western Sydney University, Sydney Australia
3Monash University, AUSTRALIA