Systematic Reviews · 5 authors, 4 centres
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This systematic review and meta-analysis of eight randomized controlled trials found that rice bran supplementation did not significantly affect serum levels of triglycerides, total cholesterol, LDL-cholesterol, or HDL-cholesterol compared to control groups.
This GRADE-assessed systematic review and meta-analysis pooled data from eight randomized controlled trials involving 369 participants to evaluate the effects of rice bran supplementation on serum lipid levels. The meta-analysis, using a random-effects model, reported weighted mean differences (WMD) for triglycerides (WMD: -11.38 mg/dl), total cholesterol (WMD: -0.68 mg/dl), LDL-cholesterol (WMD: -1.68 mg/dl), and HDL-cholesterol (WMD: 0.16 mg/dl), none of which were statistically significant (P > 0.17 for all). Subgroup analysis suggested a possible significant effect on triglycerides in studies with mixed-gender participants or participants older than 50, but this was attributed to a single high-dose study. The authors conclude that rice bran supplementation does not significantly improve lipid profiles but state that larger, longer, and higher-quality studies are needed.
