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TL;DR
This cross-sectional study of 436 Polish adults aged 50–80 found that decreased femoral bone mineral density was significantly associated with age-related macular degeneration in men but not in women.
PLOS ONE · 13 authors, 6 centres
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This cross-sectional study of 436 Polish adults aged 50–80 found that decreased femoral bone mineral density was significantly associated with age-related macular degeneration in men but not in women.
AMD prevalence was 10.8% overall (9.9% in women, 12.0% in men), and decreased BMD was found in 36.9% of women and 18.9% of men. Significant differences in femoral BMD and femur T-scores between AMD and non-AMD groups were detected only in men (mean difference = 0.11; p = 0.012 for femoral BMD; and 0.73; p = 0.011 for femur T-score). No associations between BMD and AMD were observed in women. The cross-sectional design limits causal inference, and the relatively small sample of AMD-positive men warrants confirmation.