SEARCHNARRATIVE_REVIEWnutrition, immunology

narrative_review·nutrition, immunology, endocrinology, preclinical research, public health·PMC10295324

The Preventive Mechanisms of Bioactive Food Compounds against Obesity-Induced Inflammation

Antioxidants · 4 authors, 2 centres

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TL;DR

A key limitation noted is that more clinical studies are warranted to establish effective strategies for bioactive food compound intake.

Full summary

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A key limitation noted is that more clinical studies are warranted to establish effective strategies for bioactive food compound intake. The implications suggest that targeting these compounds could represent a new approach for prevention and treatment.

STUDY TYPE

narrative_review

SPECIALTY

nutrition

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AI pipeline

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100% · A

ORIGINAL PAPER

PMC10295324

The Preventive Mechanisms of Bioactive Food Compounds against Obesity-Induced Inflammation

Antioxidants

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ABSTRACT

Abstract Dietary patterns are promising strategies for preventing and treating obesity and its coexisting inflammatory processes. Bioactive food compounds have received considerable attention due to their actions against obesity-induced inflammation, with limited harmful side effects. They are perceived as food ingredients or dietary supplements other than those necessary to meet basic human nutritional needs and are responsible for positive changes in the state of health. These include polyphenols, unsaturated fatty acids, and probiotics. Although the exact mechanisms of bioactive food compounds’ action are still poorly understood, studies have indicated that they involve the modulation of the secretion of proinflammatory cytokines, adipokines, and hormones; regulate gene expression in adipose tissue; and modify the signaling pathways responsible for the inflammatory response. Targeting the consumption and/or supplementation of foods with anti-inflammatory potential may represent a new approach to obesity-induced inflammation treatment. Nevertheless, more studies are needed to evaluate strategies for bioactive food compound intake, especially times and doses. Moreover, worldwide education about the advantages of bioactive food compound consumption is warranted to limit the consequences of unhealthy dietary patterns. This work presents a review and synthesis of recent data on the preventive mechanisms of bioactive food compounds in the context of obesity-induced inflammation. Keywords: inflammation, obesity, bioactive food compounds, polyphenols, omega-3 fatty acids, probiotics

CITATION EXPORT

Marta Pelczyńska, Małgorzata Moszak, Agnieszka Wesołek et al.. The Preventive Mechanisms of Bioactive Food Compounds against Obesity-Induced Inflammation. Antioxidants. (2023). https://doi.org/10.3390/antiox12061232

AUTHORS

4 · 2 CENTRES

Marta Pelczyńska, Małgorzata Moszak, Agnieszka Wesołek, Paweł Bogdański

1Chair and Department of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, 84 Szamarzewskiego Street, 60-569 Poznań, Poland
2Doctoral School, Poznan University of Medical Sciences, 10 Fredry Street, 61-701 Poznań, Poland