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TL;DR
The authors reviewed studies demonstrating an association between gut microbiome dysbiosis and liver diseases, including HCC.
Cureus · 7 authors, 2 centres
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The authors reviewed studies demonstrating an association between gut microbiome dysbiosis and liver diseases, including HCC.
The authors reviewed studies demonstrating an association between gut microbiome dysbiosis and liver diseases, including HCC. Key findings indicate that dysbiosis plays a role in HCC development, can serve as a diagnostic and prognostic marker, and affects the response to HCC immunotherapy. The review suggests dysbiosis may be leveraged for early detection and that antibiotics and probiotics could be part of treatment strategies. Limitations noted by the authors include the need for more human trials with larger and more diverse populations.