International Journal of Biological Sciences · 5 authors, 2 centres
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The authors detail how the pathway's activity is context-dependent, influencing tumor progression through angiogenesis, immune suppression, and metabolic changes, while also noting contradictory findings that may arise from environmental and disease-stage variability.
The authors detail how the pathway's activity is context-dependent, influencing tumor progression through angiogenesis, immune suppression, and metabolic changes, while also noting contradictory findings that may arise from environmental and disease-stage variability. The implications are that while targeting this pathway is a promising area for personalized medicine, its complex biology presents significant challenges for safe and effective clinical translation.
