Pharmaceuticals · 10 authors, 8 centres
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This narrative review synthesizes preclinical and translational research on the use of naturally derived cannabinoids in topical and transdermal formulations for skin conditions and systemic delivery. Topical cannabinoids showed local analgesic, antipruritic, anti-inflammatory, and antibacterial actions in reviewed studies, but the authors conclude that more research is required to fully understand their efficacy and safety.
The review covers preclinical and translational evidence on the pharmacological actions of cannabinoids in the skin, including local analgesic, antipruritic, anti-inflammatory, cicatrizing, and antibacterial effects. The review notes that topical cannabinoid formulations demonstrate a favorable safety profile compared to conventional treatments.
