SEARCHRCTpediatrics, nutrition

RCT·pediatrics, nutrition, clinical nutrition, public health, epidemiology·PMC10195456

Variation in outcomes of the Melbourne Infant, Feeding, Activity and Nutrition Trial (INFANT) according to maternal education and age 2 and 3·5 years post-intervention

Public Health Nutrition · 4 authors, 3 centres

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TL;DR

This cluster-randomized controlled trial followed families from the INFANT obesity prevention program for 2 and 3.5 years post-intervention to see if effects varied by maternal education and age. It found moderation for some outcomes, but no consistent patterns, suggesting the intervention was broadly effective across subgroups.

Full summary

811 CHARS

This study is a 2- and 3.5-year post-intervention follow-up of the INFANT cluster-randomised controlled trial. At 2 years, intervention effects on vegetable and sweet snack intake were greater for children with more educated mothers, while increased water intake was greater for those with less educated mothers. At 2 years, increased water consumption was greater for younger mothers, while decreased sweet snack intake was greater for older mothers. At 3.5 years, opposite trends were seen for savoury snacks. Limitations include potential bias from differential dropout and that the trial was not powered for these subgroup analyses. The authors conclude that despite some moderation, clear patterns were not evident, indicating the intervention was largely effective regardless of maternal education or age.

STUDY TYPE

RCT

SPECIALTY

pediatrics

SUMMARISED BY

AI pipeline

FIDELITY CHECK

100% · A

ORIGINAL PAPER

PMC10195456

Variation in outcomes of the Melbourne Infant, Feeding, Activity and Nutrition Trial (INFANT) according to maternal education and age 2 and 3·5 years post-intervention

Public Health Nutrition

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ABSTRACT

Abstract Objective: This study aimed to assess whether the long-term effectiveness of the Melbourne Infant, Feeding, Activity and Nutrition Trial (INFANT) at 2 and 3·5 years post-intervention varied according to maternal education and age. Design: Two and 3·5 years post-intervention follow-up of the INFANT cluster-randomised controlled trial. Outcomes at both follow-ups included children’s BMI z -scores, physical activity (ActiGraph), television viewing (parental report) and dietary intake (3 × 24-h dietary recalls). Dichotomous moderator variables included maternal education (university v . no university) and age (< 32 v . ≥ 32 years). Setting: Population based. Participants: Families completing the 15-month programme ( n 492) were invited to participate in the follow-ups when their child was 3·6 and 5 years old. Results: At the 2-year follow-up, the intervention effects on vegetable (positive) and sweet snack (negative) intake were greater in children with higher educated mothers, whereas water consumption (positive) was greater in children with lower educated mothers. At the 2-year follow-up, the intervention was more effective in increasing water consumption in children with younger mothers and decreasing sweet snack intake in children with older mothers (opposite result observed at the 3·5-year follow-up). At the 3·5-year follow-up, children with younger and older mothers increased and decreased their consumption of savoury snacks, respectively. Conclusions: Moderation by maternal education and age were observed for some outcomes; however, clear patterns were not evident at both follow-ups, with little consistency across outcomes. This indicates that INFANT was more-or-less equally effective in children irrespective of their mother’s education level or age, which is important in community-based interventions. Keywords: Children, Long-term follow-up, Moderation, Nutrition, Physical activity

CITATION EXPORT

Christine Delisle Nyström, Adrian J Cameron, Karen J Campbell et al.. Variation in outcomes of the Melbourne Infant, Feeding, Activity and Nutrition Trial (INFANT) according to maternal education and age 2 and 3·5 years post-intervention. Public Health Nutrition. (2021). https://doi.org/10.1017/S1368980021000045

AUTHORS

4 · 3 CENTRES

Christine Delisle Nyström, Adrian J Cameron, Karen J Campbell, Kylie D Hesketh

1Department of Biosciences and Nutrition, Karolinska Institutet, Neo, Huddinge 141 83, Sweden
2Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, Australia
3Global Obesity Centre, Institute for Health Transformation, Deakin University, Geelong, Australia